People
Research Interests
My research investigates the effects of physical fitness and exercise on the immune system, with the long-term goal of understanding how physical fitness and exercise can improve diseases and conditions associated with immune dysregulation, such as cancer. I am also interested in how physical fitness and exercise can mitigate the impact of stress on the immune system.
Recent Publications and Research Activity
Hodgman, C.F. Hunt, R.M., Crane, J.C. Elzayat, M.T., LaVoy, E.C. (2023) A Scoping Review on the Effects of Physical Exercise and Fitness on Peripheral Leukocyte Energy Metabolism. Exerc Immunol Rev. 29:54-87 PMID: 37358364
Hunt, R., Elzayat, M., Laughlin, M., Markofski, M.M., LaVoy, EC. (2023) Characterization of Transitional Memory CD4+ and CD8+ T-cell Mobilization During and After an Acute Bout of Exercise. Frontiers in Sports and Active Living, https://doi.org/10.3389/fspor.2023.1120454
Crane, J., Gordon, M., Basen-Engquist, K., Ferrajoli, A., Markofski, M.M., Young, C., Fares, S., Simpson, R., LaVoy, E.C. (2023) Relationships between T-lymphocytes and physical function in adults with chronic lymphocytic leukemia: results from the HEALTH4CLL pilot study. European Journal of Haematology https://doi.org/10.1111/ejh.13958
Savage, H., Pareek, S., Lee, J., Ballaro, R., Minussi, D.C., Hayek, K., Sadullozoda, M., Lochmann, B., McQuade, J., LaVoy, E., Marmonti, E., Patel, H., Wang, G., Imanishi, M., Kotla, S., Abe, J., Schadler, K. (2023) Aerobic exercise alters the melanoma microenvironment and modulates ERK5 S496 phosphorylation. Cancer Immunology Research https://doi.org/10.1158/2326-6066.CIR-22-0465
Batatinha, H., Diak, D., Niemiro, G., Baker, F., Smith, K., Zúñiga, T., Mylabathula, P., Seckeler, M., Lau, B., LaVoy, E.C., Gustafson, M., Katsanis, E., Simpson, R.J. (2023) Human lymphocytes mobilized with exercise have an anti-tumor transcriptomic profile and exert enhanced graft-versus-leukemia effects in xenogeneic mice. Front Immunol https://doi.org/10.3389/fimmu.2023.1067369
Gupta P, Hodgman CF, Alvarez-Florez C, Schadler KL, Markofski MM, O'Connor D.P., LaVoy, E.C. (2022) Comparison of three exercise interventions with and without gemcitabine treatment on pancreatic tumor growth in mice: No impact on tumor infiltrating lymphocytes. Front Physiol. [https://doi:10.3389/fphys.2022.1039988]https://doi:10.3389/fphys.2022.1039988
Hodgman, C.F., LaVoy, E.C., Johnston, C.A., Obasi, E., Murillo R., Yan S., O’Connor D.P., McNeill, L. Reitzel, L.R., Hernandez, D.C. (2022) Measuring pro- and anti-inflammatory biomarkers among low-income Hispanic adults: a feasibility and pilot assessment. Health Behavior Research Vol. 5: No. 3. https://doi.org/10.4148/2572-1836.1143
Graff, R.M., Jennings, K., LaVoy, E.C., Warren, V., Macdonald, B., Park, Y., Markofski, M. (2022) T-cell counts in response to acute cardiorespiratory or resistance exercise in physically active or physically inactive older adults: A randomized crossover study. Journal of Applied Physiology [https://doi:10.1152/japplphysiol.00301.2021]https://doi:10.1152/japplphysiol.00301.2021
Gupta, P., Hodgman, C.F., Schadler, K.L., LaVoy, E.C. (2022) Effect of exercise on pancreatic cancer patients during treatment: A scoping review of the literature. Supportive Care in Cancer https://doi.org/10.1007/s00520-022-06925-7
Markofski, M.M., Jennings, K., Hodgman, C.F., Warren, V.E., LaVoy, E.C. (2021) Physical activity during the SARS-CoV-2 pandemic is linked to better mood and emotion. Stress & Health https://doi.org/10.1002/smi.3111
Elzayat, M.T., Markofski, M.M., Simpson, R.J., Laughlin, M., LaVoy, E.C (2021) No effect of acute eccentric resistance exercise on immune responses to Influenza vaccination in older adults: a randomized control trial. Frontiers in Physiology https://doi.org/10.3389/fphys.2021.713183
Reesor-Oyer, L., Murillo, R., LaVoy, E.C., O’Connor, D.P., Liu, Y., Hernandez, D.C. (2021) The role of leisure time physical activity and sedentary behavior in the income-overweight/obesity relationship. International Journal of Environmental Research and Public Health https://doi.org/10.3390/ijerph18063127
Graff, R., Jennings, K., Davies, N., Carrillo, A., LaVoy, E.C., Ryan, E.J., Markofski, M. (2021) A short-term paleolithic dietary intervention does not alter adipokines linked to adiposity. International Journal of Exercise Science https://digitalcommons.wku.edu/ijes/vol14/iss2/3
LaVoy, E.C., Palmer, C.A., So, C., Alfano, C.A. (2020) Bidrectional relationships between sleep and biomarkers of stress and immunity in youth. International Journal of Psychophysiology https://doi.org/10.1016/j.ijpsycho.2020.10.010
Kunz, H.E., Agha, N.H., LaVoy, E.C., Hussain, M., Smith, K.A., Mylabathula, P., Diak, D., Baker, F.L., O'Connor, D. P., Bond, R.A., Katsanis, E., Bollard, C.M. Simpson, R.J. (2020) The effects of β1 and β1+2 adrenergic receptor blockade on the exercise-induced mobilization and ex vivo expansion of virus-specific T-cells: implications for cellular therapy and the anti-viral immune effects of exercise. Cell Stress and Chaperones https://doi.org/10.1007/s12192-020-01136-7
Lee, J., Hong, J. Umetani, M., LaVoy, E.C., Kim, J., Park, Y. (2020) Vascular protection by exercise in obesity: inflammasome-associated mechanisms. Medicine & Science in Sports & Exercise https://doi.org/10.1249/MSS.0000000000002419
Education
B.S. in Biology at Northern Michigan University, 2005
M.S. in Biology at Northern Michigan University, 2008
Ph.D. in Kinesiology at University of Houston, 2014